Weimaraners are fast and powerful dogs, but are also suitable home animals given appropriate training & exercise. These dogs are not as sociable towards strangers as other hunting dogs such as Labradors and Golden Retrievers. Weimaraners are very protective of their family and can be very territorial. They can be aloof to strangers, and must be thoroughly socialized when young to prevent aggression. They are also highly intelligent, sensitive and problem-solving animals, which earned them an epithet "dog with a human brain". From adolescence, a Weimaraner requires extensive exercise in keeping with an energetic hunting dog breed and prized for their physical endurance and stamina. No walk is too far, and they will appreciate games and play in addition. An active owner is more likely to provide the vigorous exercising, games, or running that this breed absolutely requires. Weimaraners are high-strung and often wear out their owners, requiring appropriate training to learn how to calm them and to help them learn to control their behavior. Owners need patience and consistent, firm (yet kind) training, as this breed is particularly rambunctious during the first year and a half of its life. Like many breeds, untrained and unconfined young dogs often create their own fun when left alone, such as chewing house quarters and furniture. Thus, many that are abandoned have behavioural issues as a result of isolation and inferior exercise.

It should never be forgotten that the Weimaraner is a hunting dog and therefore has a strong, instinctive prey drive. Weimaraners will sometimes tolerate cats, as long as they are introduced to the cats as puppies, but many will chase and frequently kill almost any small animal that enters their garden or backyard. In rural areas, most Weimaraners will not hesitate to chase deer or sheep. However, with good training, these instincts can be curtailed to some degree. A properly trained Weimaraner is a wonderful companion that will never leave its master's side.